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Of those Atgs, Beclin one, the mammalian ortholog of yeast Atg6, interacts with class III PI3K (also named Vps34) and so plays a crucial function while in the initiation of autophagosome formation through autophagy7. Beclin one is the 1st autophagy-related tumor suppressor gene noted thus far, and it has been shown to stimulate autophagy and suppre